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I6658

Isradipine

Name: Isradipine
Brand: SIGMA

≥98% (HPLC), calcium channel blocker, solid

Synonym(s):

4-(4-Benzofurazanyl)-1,-4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid methyl 1-methylethyl ester

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About This Item

Empirical Formula (Hill Notation):

C₁₉H₂₁N₃O₅

CAS Number:

75695-93-1

Molecular Weight:

371.39

UNSPSC Code:

12352200

PubChem Substance ID:

24724517

NACRES:

NA.77

MDL number:

MFCD00153820

Assay:

≥98% (HPLC)

Form:

solid

Quality level:

100

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Properties

Product Name

Isradipine, ≥98% (HPLC), solid

description

Store under nitrogen

Quality Level

100

assay

≥98% (HPLC)

form

solid

color

yellow

solubility

DMSO: >10 mg/mL

originator

Novartis

storage temp.

2-8°C

SMILES string

COC(=O)C1=C(C)NC(C)=C(C1c2cccc3nonc23)C(=O)OC(C)C

InChI

1S/C19H21N3O5/c1-9(2)26-19(24)15-11(4)20-10(3)14(18(23)25-5)16(15)12-7-6-8-13-17(12)22-27-21-13/h6-9,16,20H,1-5H3

InChI key

HMJIYCCIJYRONP-UHFFFAOYSA-N

Gene Information

human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779), CACNA2D1(781)

Description

Application

Isradipine has been used to explore neuroprotective activity.

Biochem/physiol Actions

Isradipine is considered as an active calcium channel blocker, used to treat hypertension.

L-type calcium channel blocker (also referred to as dihydropyridine-type calcium channel blocker); antihypertensive.

L-type calcium channel blocker; antihypertensive.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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