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Merck
CN

M0164

MES hemisodium salt

dry powder

Synonym(s):

2-(N-Morpholino)ethanesulfonic acid hemisodium salt, 4-Morpholineethanesulfonic acid hemisodium salt

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About This Item

Empirical Formula (Hill Notation):
C6H13NO4S·0.5Na
CAS Number:
Molecular Weight:
206.73
UNSPSC Code:
12161700
eCl@ss:
32129211
PubChem Substance ID:
NACRES:
NA.25
MDL number:
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form

dry powder

Quality Level

useful pH range

5.5-6.7

pKa 

6.1

SMILES string

[Na+].OS(=O)(=O)CCN1CCOCC1.[O-]S(=O)(=O)CCN2CCOCC2

InChI

1S/2C6H13NO4S.Na/c2*8-12(9,10)6-3-7-1-4-11-5-2-7;/h2*1-6H2,(H,8,9,10);/q;;+1/p-1

InChI key

KHQSUKMBWPKXOP-UHFFFAOYSA-M

General description

MES sodium salt is commonly employed as buffer.

Application

MES hemisodium salt may be employed as buffer to investigate the two-dimensional and three-dimensional (3D) patterns within multilayered poly(ethylene glycol) diacrylate (PEG-DA) hydrogels.

Packaging

foil pouches

Preparation Note

Contents of each pouch dissolved in 1 liter deionized water will yield 0.1 M sodium MES buffer, pH 6.1 at 25°C.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Georgia Papavasiliou et al.
Tissue engineering. Part C, Methods, 14(2), 129-140 (2008-05-13)
Photopolymerizable hydrogels have been investigated extensively for biomedical applications, specifically in the area of tissue engineering. While fabrication approaches have shown promise in designing hydrogel scaffolds that guide cell function, the ability to spatially control localization in three-dimensions has been
Nicholas Sofos et al.
Molecular cell, 79(5), 741-757 (2020-07-31)
Cmr-β is a type III-B CRISPR-Cas complex that, upon target RNA recognition, unleashes a multifaceted immune response against invading genetic elements, including single-stranded DNA (ssDNA) cleavage, cyclic oligoadenylate synthesis, and also a unique UA-specific single-stranded RNA (ssRNA) hydrolysis by the
Magnus Rogeberg et al.
Biochimie, 105, 216-220 (2014-07-11)
Deposition of insoluble amyloid plaques is one of the known hallmarks of Alzheimer's disease. Amyloid beta 1-42 is the main component in these plaques, and the soluble oligomers of this peptide are believed to contribute to synaptic degradation and dementia.



Global Trade Item Number

SKUGTIN
M0164-10PAK04061833992586
M0164-5X10PAK04061833992593