M3324
M100907
≥98% (HPLC), 5-HT2A Antagonist, powder
Synonym(s):
(R)-(+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-pipidinemethanol, MDL100907, Volinanserin
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About This Item
Empirical Formula (Hill Notation):
C22H28FNO3
CAS Number:
Molecular Weight:
373.46
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Product Name
M100907, ≥98% (HPLC)
Quality Level
assay
≥98% (HPLC)
form
powder
color
off-white to light brown
solubility
DMSO: ≥20 mg/mL
storage temp.
2-8°C
SMILES string
COc1cccc([C@H](O)C2CCN(CC2)CCc3ccc(F)cc3)c1OC
InChI
1S/C22H28FNO3/c1-26-20-5-3-4-19(22(20)27-2)21(25)17-11-14-24(15-12-17)13-10-16-6-8-18(23)9-7-16/h3-9,17,21,25H,10-15H2,1-2H3/t21-/m1/s1
InChI key
HXTGXYRHXAGCFP-OAQYLSRUSA-N
Gene Information
human ... HTR2A(3356)
General description
M100907 blocks the serotonin 2A (5-HT2A) receptors and imposes antidepressant-like effects. It may be used for treating dopaminergic anomalies.
Biochem/physiol Actions
M100907 is a selective 5-HT2A Antagonist.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
我们提供许多血清素受体相关产品，满足您的各类研究需求。
We offer many products related to serotonin receptors for your research needs.
Ashley Furr et al.
The international journal of neuropsychopharmacology, 15(9), 1295-1305 (2011-10-20)
Chronic stress is a risk factor for depression, and chronic stress can induce cognitive impairments associated with prefrontal cortical dysfunction, which are also major components of depression. We have previously shown that 5 wk chronic intermittent cold (CIC) stress induced
Kerry A Waters et al.
Behavioural brain research, 228(1), 211-218 (2011-12-23)
The 5-hydroxytryptamine7 (5-HT7) receptor is a G-protein coupled receptor for serotonin that has been implicated in the pathophysiology of psychiatric and neurological disorders including anxiety, depression and schizophrenia. A number of studies have attempted to evaluate the potential role of
Paul J Fletcher et al.
Neuropharmacology, 61(3), 468-477 (2011-03-16)
Previous work has shown that 5-HT(2C) receptor agonists and 5-HT(2A) receptor antagonists reduce impulsive action, as well as the locomotor stimulant effect of psychomotor stimulants. Since psychomotor stimulants also increase impulsive action we examined the effects of the 5-HT(2C) receptor
Global Trade Item Number
| SKU | GTIN |
|---|---|
| M3324-25MG | 04061832072227 |
| M3324-5MG | 04061834050131 |