Skip to Content
Merck
CN

Key Documents

View All Documentation

M4145

Minoxidil

≥99% (TLC), powder, potassium channel activator

Synonym(s):

6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide, 6-(1-Piperidinyl)pyrimidine-2,4-diamine 3-oxide

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C9H15N5O
CAS Number:
38304-91-5
Molecular Weight:
209.25
NACRES:
NA.77
PubChem Substance ID:
24277853
UNSPSC Code:
12352200
EC Number:
253-874-2
MDL number:
MFCD00063409
Assay:
≥99% (TLC)
Quality level:
100
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Minoxidil, ≥99% (TLC)

Quality Level

100

assay

≥99% (TLC)

mp

272-274 °C (dec.) (lit.)

originator

Johnson & Johnson

SMILES string

NC1=CC(=NC(=N)N1O)N2CCCCC2

InChI

1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2

InChI key

ZIMGGGWCDYVHOY-UHFFFAOYSA-N

Gene Information

human ... KCNJ1(3758)

Application

Minoxidil has been used as test drug:
  • in dermal papilla spheroid model, to study the effect of hair regeneration
  • administered orally to experimental rats, in the approach to identify biomarkers of drug induced vascular injury
  • administered via oral gavage to nonhuman primate model in order to study its effect on tilt responses

Biochem/physiol Actions

Activates ATP-activated K+ channels; vasodilator; slow or stop hair loss and promote hair regrowth.
Minoxidil is originally used to treat hypertension, which also induces hypertrichosis. It is considered as a potent drug for treating androgenetic alopecia.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Still not finding the right product?

Explore all of our products under Minoxidil

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library