N3018
(±)-Nornicotine
≥98% (TLC), Nicotinic acetylcholine receptor agonist, liquid
Synonym(s):
2-(3-Pyridyl)pyrrolidine, 3-(2-Pyrrolidinyl)pyridine
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About This Item
Empirical Formula (Hill Notation):
C9H12N2
CAS Number:
Molecular Weight:
148.20
UNSPSC Code:
12352210
eCl@ss:
39151701
PubChem Substance ID:
NACRES:
NA.77
Beilstein/REAXYS Number:
81968
MDL number:
Product Name
(±)-Nornicotine, ≥98% (TLC), liquid
Quality Level
assay
≥98% (TLC)
form
liquid
color
yellow
solubility
H2O: 20 mg/mL
storage temp.
2-8°C
SMILES string
C1CNC(C1)c2cccnc2
InChI
1S/C9H12N2/c1-3-8(7-10-5-1)9-4-2-6-11-9/h1,3,5,7,9,11H,2,4,6H2
InChI key
MYKUKUCHPMASKF-UHFFFAOYSA-N
Gene Information
mouse ... Chrna1(11435), Chrna7(11441)
rat ... Chrna4(25590)
Application
(±)-Nornicotine has been used as a neat alkaloid standard to demonstrate the mechanistic role that oxides of nitrogen have in tobacco-specific nitrosamines formation.
Biochem/physiol Actions
Nornicotine, an active metabolite of nicotine, is a nicotinic acetylcholine receptor agonist. Nornicotine is a minor alkaloid of tobacco leaves that serves as a precursor of a carcinogen, N-nitrosonornicotine. N-Demethylation of nicotine gives nornicotine, which occurs especially during tobacco leaf senescence and curing.
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Regulatory Information
涉药品监管产品
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