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P5172

Prostaglandin D2

synthetic, ≥95%, adenylyl cyclase stimulator, powder

Synonym(s):

(5Z,9α,13E,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic-acid, PGD2

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About This Item

Empirical Formula (Hill Notation):
C20H32O5
CAS Number:
41598-07-6
Molecular Weight:
352.47
UNSPSC Code:
12352211
eCl@ss:
42020658
PubChem Substance ID:
24898605
NACRES:
NA.77
Beilstein/REAXYS Number:
2170623
MDL number:
MFCD00077857
Assay:
≥95%
Form:
powder
Quality level:
100
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Product Name

Prostaglandin D2, ≥95%, synthetic

biological source

synthetic

Quality Level

100

assay

≥95%

form

powder

storage temp.

−20°C

SMILES string

[H][C@]1(C\C=C/CCCC(O)=O)[C@@H](O)CC(=O)[C@]1([H])\C=C\[C@@H](O)CCCCC

InChI

1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1

InChI key

BHMBVRSPMRCCGG-OUTUXVNYSA-N

Biochem/physiol Actions

Primary prostaglandin in brain; induces inflammation; stimulates adenylyl cyclase.

Features and Benefits

This compound is featured on the Prostanoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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wgk

WGK 3

flash_point_f

Not applicable

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

hcodes

H302,H360

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ9648
MKCQ4174
MKCP0239
MKCD7725
MKBZ7060V

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S O'Sullivan et al.
The Journal of allergy and clinical immunology, 98(2), 421-432 (1996-08-01)
Prostaglandin (PG)D2 is a major product of arachidonic acid metabolism in pulmonary mast cells. We therefore attempted to determine whether measurement of the stable urinary metabolite of PGD2, 9 alpha, 11 beta-PGF2, could serve as a marker of mast cell
Roy Pettipher et al.
Nature reviews. Drug discovery, 6(4), 313-325 (2007-03-31)
Immunological activation of mast cells is an important trigger in the cascade of inflammatory events leading to the manifestation of allergic diseases. Pharmacological studies using the recently discovered DP(1) and CRTH2 antagonists combined with genetic analysis support the view that
P Gresele et al.
Biochemical pharmacology, 33(13), 2083-2088 (1984-07-01)
Dazoxiben, a thromboxane synthase inhibitor, inhibits arachidonic acid induced aggregation in platelet-rich plasma from some donors only ("responders"). We have studied the effect of dazoxiben in vitro on platelet aggregation and prostaglandin (PG) metabolism and the influence of the incubation
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Global Trade Item Number

SKUGTIN
P5172-10MG04061832785851
P5172-1MG04061834376750
P5172-5MG04061832785868