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P6777

Phenelzine sulfate salt

synthetic, ≥98% (iodine, titration), MAO-A/B inhibitor, powder

Synonym(s):

Phenelzine hydrogen sulphate

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About This Item

Empirical Formula (Hill Notation):
C8H12N2 · H2O4S
CAS Number:
156-51-4
Molecular Weight:
234.27
NACRES:
NA.77
PubChem Substance ID:
24278646
UNSPSC Code:
12352200
EC Number:
205-856-0
MDL number:
MFCD00050687
Assay:
≥98% (iodine, titration)
Form:
powder
Quality level:
200
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Product Name

Phenelzine sulfate salt,

biological source

synthetic

Quality Level

200

assay

≥98% (iodine, titration)

form

powder

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

SMILES string

NNCCC1=CC=CC=C1.OS(=O)(O)=O

InChI

1S/C8H12N2.H2O4S/c9-10-7-6-8-4-2-1-3-5-8;1-5(2,3)4/h1-5,10H,6-7,9H2;(H2,1,2,3,4)

InChI key

RXBKMJIPNDOHFR-UHFFFAOYSA-N

Gene Information

human ... MAOA(4128), MAOB(4129)

Biochem/physiol Actions

Non-selective MAO-A/B inhibitor.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG9192
BCBN9644V
BCBX0084
BCBW2765
BCBV3266

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Articles

血清素合成及代谢

血清素（5-羟色胺）主要存在于三种主要细胞类型中：i）中杻神经系统（CNS）和肠肌间神经丛中的血清素能神经元，ii）胃肠道粘膜中的肠嗜铬细胞，和iii）血小板。血清素的代谢主要通过外部线粒体膜酶单胺氧化酶（MAO）进行，它以两种分子亚型存在，分别称为MAO-A和MAO-B。

Serotonin Synthesis & Metabolism

Serotonin is stored in cells and metabolized by MAO, influencing CNS, GI, and platelet functions.

The effect of riluzole augmentation in a patient with treatment-resistant obsessive-compulsive disorder, taking two other glutaminergic agents.
Nahla Mahgoub et al.
The Journal of neuropsychiatry and clinical neurosciences, 23(2), E24-E25 (2011-06-17)
Darrick T Balu et al.
Brain research, 1211, 37-43 (2008-04-25)
Antidepressant treatments have been proposed to produce their therapeutic effects, in part, through increasing neurotrophin levels in the brain. The current experiments investigated the effects of acute and chronic treatment with different pharmacologic and somatic antidepressant treatments on protein levels
Anna Z Antosik-Wójcińska et al.
Psychiatria polska, 47(1), 127-134 (2013-07-31)
The use of non-selective monoamine oxidase inhibitors (IMAO) may be associated with the risk of addiction, which is confirmed by case studies published so far. Harmful use of antidepressants in patients with affective disorders and anxiety is not frequent, but
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Global Trade Item Number

SKUGTIN
P6777-25G04061832948478
P6777-5G04061834394013