P8791
Polyglycine
mol wt 500-5,000
Synonym(s):
Glycine homopolymer
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About This Item
CAS Number:
UNSPSC Code:
12352202
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
MDL number:
form
lyophilized powder
Quality Level
mol wt
500-5,000
color
white to light yellow
mp
300 °C
storage temp.
−20°C
SMILES string
NCC(O)=O
InChI
1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChI key
DHMQDGOQFOQNFH-UHFFFAOYSA-N
Gene Information
rat ... Grin2a(24409)
Application
Polyglycine has been used as an external intensity standard for measuring cross polarization (CP) nuclear magnetic resonance (NMR) spectrum measurements and ion mobility mass spectrometry. It is suitable for use as a model for UV resonance Raman spectroscopy studies.
Biochem/physiol Actions
Polyglycine exists in two forms, namely the polyglycine I (PGI) with anti-parallel β-sheet structure and polyglycine II (PGII) with extended 31-helix. It is a most flexible polypeptide with minimal steric hindrance and its solubility increases in the presence of lithium ions. It is present in mammals and plants. Polyglycine stretch associated with the chloroplast membrane protein, Toc5 is essential for envelop sorting.
Preparation Note
Prepared by phosphorylation.
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.
Solid-state 15 N NMR analysis of highly 15 N-enriched plant materials
Smernik RJ and Baldock JA
Plant and Soil, 275(1-2), 271-283 (2005)
Sergei Bykov et al.
The journal of physical chemistry. B, 114(19), 6636-6641 (2010-04-27)
Polyglycine (polygly) is an important model system for understanding the structural preferences of unfolded polypeptides in solution. We utilized UV resonance and visible Raman spectroscopy to investigate the conformational preferences of polygly peptides of different lengths in water containing LiCl
Kiran Kumar Morishetti et al.
Journal of the American Society for Mass Spectrometry, 21(4), 603-614 (2010-01-29)
The sequence and conformational effects on the gas-phase acidities of peptides have been studied by using two pairs of isomeric cysteine-polyglycine peptides, CysGly(3,4)NH(2) and Gly(3,4)CysNH(2). The extended Cooks kinetic method was employed to determine the gas-phase acidities using a triple
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P8791-100MG | 04061832780771 |