P9178
Prochlorperazine dimaleate salt
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About This Item
Empirical Formula (Hill Notation):
C20H24ClN3S · 2C4H4O4
CAS Number:
Molecular Weight:
606.09
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
201-511-3
MDL number:
Form:
powder
Quality level:
form
powder
Quality Level
solubility
H2O: slightly soluble 0.3 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.3 mg/mL, methanol: soluble
originator
GlaxoSmithKline
SMILES string
OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1
InChI
1S/C20H24ClN3S.2C4H4O4/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24;2*5-3(6)1-2-4(7)8/h2-3,5-8,15H,4,9-14H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
InChI key
DSKIOWHQLUWFLG-SPIKMXEPSA-N
Gene Information
human ... DRD2(1813)
Biochem/physiol Actions
Prochlorperazine is an anti-nausea and neuroleptic agent. It is known to cause neuropsychiatric side effects. Prochlorperazine inhibits the action of dopamine in the central nervous system. It acts as an antiemetic drug and prevents vomiting and stimulates sleep. Prochlorperazine is useful as a tranquilizer in the treatment of schizophrenia and nonpsychotic anxiety.
Phenothiazine antipsychotic; D2 dopamine receptor antagonist; antispasmodic
Features and Benefits
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Lact. - Repr. 2 - STOT SE 3
target_organs
Central nervous system
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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