P9405
O-Phospho-L-tyrosine
≥95.0% (HPLC)
Synonym(s):
L-3-(4-Hydroxyphenyl)alanine 4′-phosphate, L-Tyrosine-O-phosphate
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About This Item
Empirical Formula (Hill Notation):
C9H12NO6P
CAS Number:
Molecular Weight:
261.17
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
Beilstein/REAXYS Number:
3150815
MDL number:
Product Name
O-Phospho-L-tyrosine,
assay
≥95.0% (HPLC)
Quality Level
form
powder
color
white to off-white
mp
225 °C
application(s)
cell analysis
storage temp.
−20°C
SMILES string
N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(O)=O
InChI
1S/C9H12NO6P/c10-8(9(11)12)5-6-1-3-7(4-2-6)16-17(13,14)15/h1-4,8H,5,10H2,(H,11,12)(H2,13,14,15)/t8-/m0/s1
InChI key
DCWXELXMIBXGTH-QMMMGPOBSA-N
Application
O-Phospho-L-tyrosine has been used:
- as a diluent of anti-phosphotyrosine antibody to study sperm capacitation
- as an amino acid standard in liquid chromatography with tandem mass spectrometry (LC-MS-MS) analysis
- as an amino acid standard in two-dimensional thin-layer electrophoresis system to analyze phosphoamino acids on the phosphorylated starch phosphorylase (L-SP)
Biochem/physiol Actions
Phosphotyrosine acts as a docking site in protein regulation by stimulating interaction between tyrosine-phosphorylated proteins and phosphotyrosine domains of other proteins.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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