Rabbit anti-RNA Polymerase II Antibody, Affinity Purified

The epitope recognized by PLA0127 maps to the C-terminal repeat of human RNA Polymerase II (GeneID 5430).

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

The RNA polymerase II subunit B1 (RPB1) is the largest subunit of the RNA polymerase II core complex. RNA polymerase II holoenzyme functions to transcribe DNA into messenger RNA in eukaryotes. RPB1 forms the DNA binding domain of the polymerase that forms a cleft that grabs the incoming DNA template to translocate the holoenzyme across the RNA-DNA hybrid.

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