Recommended Products
Assay
≥95% (HPLC)
form
powder or crystals
color
Reddish-brown
pKa
1.7 (4-hydroxyl group)
7.9 (4-piperazine nitrogen)
pI
4.84
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
mycobacteria
viruses
Mode of action
protein synthesis | interferes
storage temp.
−20°C
SMILES string
CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(\C=N\N5CCN(C)CC5)c(O)c4c3C2=O
InChI
1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1
InChI key
JQXXHWHPUNPDRT-WLSIYKJHSA-N
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Related Categories
General description
Application
Biochem/physiol Actions
Other Notes
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Regulatory Information
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Aldrich Products
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What is the Department of Transportation shipping information for this product?
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How is the potency determined for Product R3501, Rifampicin?
The potency is determined from a microbiological assay (USP XXII) for antibiotics, a 2-level assay. The test organism is Bacillus subtilis ATCC 6633. The minimum dose is 4.0 μg/ml and the maximum dose is 8.0 μg/ml.
The label advises that I should store Product R3501, Rifampicin, frozen. But when it arrived there was no ice in the package. Why is that?
This product in its powder form is stable for short periods of time (i.e., the shipping process), at ambient temperature. For long term storage it is best to store it at -20°C.
What is the difference between the various Rifampicin products available from Sigma-Aldrich?
Sigma-Aldrich offers several Rifampicin products, each tested and best suited for specific applications. The products range from a general use research grade to sterile powder, to plant culture tested. See individual products for specific details.
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