RAB0431
Mouse Shh-N ELISA Kit
for serum, plasma and cell culture supernatant
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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
mouse ... Shh(20423)
Input:
sample type cell culture supernatant(s)
sample type serum
sample type plasma
sample type serum
sample type plasma
Species reactivity:
mouse
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, capture ELISA: suitable
input
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 4.1-1000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Shh(20423)
General description
The Mouse Shh-N (Sonic Hedgehog N Terminus) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse Shh-N in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Mouse Sonic Hedgehog (N-terminus)
Application
For research use only. Not for use in diagnostic procedures.
Mouse Shh-N ELISA Kit has been used to measure serum sonic hedgehog (Shh) level.
Mouse Shh-N ELISA Kit has been used to measure serum sonic hedgehog (Shh) level.
Biochem/physiol Actions
Sonic hedgehog (Shh) is a secreted glycoprotein involved in embryonic morphogenic development of several tissues. It has a role in fracture healing and regeneration. In the canonical pathway, the protein associates with its receptor Patched (Ptc-1), de-represses Smoothened (Smo) and activates the Gli family of transcription factors. Mutations in the Shh pathway have been linked to developmental diseases and cancer. Shh plays a vital role in axon growth and guidance throughout the brain development. Shh stimulates neurite outgrowth by overcoming neurite growth inhibitory environment associated with glial scar.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
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Kit Components Also Available Separately
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SDS & Pricing
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
10 - Combustible liquids
Regulatory Information
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Related Content
Reduced lipoapoptosis, hedgehog pathway activation and fibrosis in caspase-2 deficient mice with non-alcoholic steatohepatitis.
Machado MV
Gut, 64(7), 1148-1157 (2015)
An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth.
Shi X
Nature Communications, 5:5425-5:5425 (2014)
Sonic hedgehog stimulates neurite outgrowth in a mechanical stretch model of reactive-astrogliosis.
Berretta A
Scientific Reports, 6:21896-6:21896 (2016)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| RAB0431-1KT | 04061834962540 |