RAB0460
Human TGF-β 1 ELISA Kit
for serum, plasma, and cell culture supernatants
Synonym(s):
TGF-beta-1, Transforming growth factor beta-1
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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... TGFB1(7040)
Input:
sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type cell culture supernatant(s)
sample type plasma
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, capture ELISA: suitable
input
sample type serum
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/mL
standard curve range: 0.0823-60 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... TGFB1(7040)
General description
The Human TGF-β 1 ELISA (Enzyme-Linked mmunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human TGF-β 1 in serum, plasma, cell culture supernatants.
Immunogen
Recombinant Human TGF-β 1
Application
For research use only. Not for use in diagnostic procedures.
Human transforming growth factor-β1 (TGF-β1) ELISA Kit has been used to measure level of TGF-β1 released from tubular cells.
Human transforming growth factor-β1 (TGF-β1) ELISA Kit has been used to measure level of TGF-β1 released from tubular cells.
Biochem/physiol Actions
Transforming growth factor-β1 (TGF-β1) is a pluripotential cytokine that plays a vital role in the homeostasis of peripheral CD4+CD25+ regulatory T cells and regulation of FOXP3 (forkhead box P3) expression in vivo. Binding of TGF-β1 to its receptor, activates members of the SMAD protein family involved in gene regulation. Study shows that reduced expression of circulating transforming growth factor-β1 (TGF-β1) might contribute to systemic lupus erythematosus (SLE) development. Polymorphism of TGF-β1 is associated with pathogenesis of rheumatoid arthritis (RA) and pneumoconiosis. Serum TGF-β1 expression is elevated in systemic sclerosis (SSc) patients. Serum TGF-β1 functions as a potential biomarker of Guillain-Barré syndrome (GBS) and SSc.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Kit Components Also Available Separately
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Description
SDS & Pricing
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Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
10 - Combustible liquids
Regulatory Information
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Related Content
Association between Genetic Variants of Transforming Growth Factor-?1 and Susceptibility of Pneumoconiosis: A Meta-analysis.
Deng CW
Chinese Medical Journal (English Edition), 130(3), 357-364 (2017)
Increased serum concentrations of transforming growth factor-?1 (TGF-?1) in patients with Guillain-Barre syndrome.
Chang KH
Clinica Chimica Acta; International Journal of Clinical Chemistry, 461, 8-13 (2016)
Reassessing the Role of the Active TGF-?1 as a Biomarker in Systemic Sclerosis: Association of Serum Levels with Clinical Manifestations.
Dantas AT
Disease Markers (2016)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| RAB0460-1KT | 04061834962717 |