RAB0817
Mouse Ins1 / Insulin-1 ELISA Kit
for serum, plasma and cell culture supernatants
Synonym(s):
Ins1
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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
mouse ... Ins1(16333)
Input:
sample type plasma
sample type serum
sample type cell culture supernatant(s)
sample type serum
sample type cell culture supernatant(s)
Species reactivity:
mouse
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type serum
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 μIU/mL
standard curve range: 6.25-400 μIU/ml
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Ins1(16333)
General description
The antibody pair provided in this kit recognizes Mouse Insulin 1.
Application
Mouse Ins1 / Insulin-1 ELISA Kit has been used to measure changes in serum insulin in male Sprague-Dawley rats with chemically induced diabetes.
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Certain organisms such as mice, rat and xenopus possess two non-allelic insulin genes. These genes are Ins1 and Ins2, which are both functional. They encode insulin that is produced in a 1:2 ratio, respectively in the pancreas. The two genes are differentially expressed in mouse. The Ins1 gene maps to mouse chromosome 19 in the telomeric region. The insulin that is synthesized in the pancreas is crucial in maintaining glucose homeostasis. Knockout of Ins-1 and Ins-2 leads to insulin deficient mice with diabetes mellitus, ketoacidosis, liver steatosis and retarded growth.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Kit Components Also Available Separately
Product No.
Description
SDS & Pricing
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
常规特殊物品
低风险生物材料
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Differential expression and imprinting status of Ins1 and Ins2 genes in extraembryonic tissues of laboratory mice.
Deltour L, et al.
Gene expression patterns : GEP, 5(2), 297-300 (2004)
Phenotypic alterations in insulin-deficient mutant mice.
Duvillie B, et al.
Proceedings of the National Academy of Sciences of the USA, 94(10), 5137-5140 (1997)
David P Labbé et al.
Nature communications, 10(1), 4358-4358 (2019-09-27)
Systemic metabolic alterations associated with increased consumption of saturated fat and obesity are linked with increased risk of prostate cancer progression and mortality, but the molecular underpinnings of this association are poorly understood. Here, we demonstrate in a murine prostate
Global Trade Item Number
| SKU | GTIN |
|---|---|
| RAB0817-1KT | 04061835165940 |