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S1820

Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt

≥98% (HPLC), Thrombin receptor activating peptide, lyophilized powder

Synonym(s):

PAR-1 (Protease-Activated Receptor) Selective Activating Peptide, PAR1-AP, SFLLRN-NH2

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About This Item

Linear Formula:
C34H57N11O8 · x CF3COOH
CAS Number:
141923-40-2
Molecular Weight:
747.89 (free base basis)
UNSPSC Code:
12352200
PubChem Substance ID:
329824491
NACRES:
NA.32
MDL number:
MFCD18782166
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Product Name

Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt, ≥98% (HPLC), lyophilized powder

Quality Level

100

assay

≥98% (HPLC)

form

lyophilized powder

color

white

UniProt accession no.

P08069

storage temp.

−20°C

SMILES string

OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(N)=O

InChI

1S/C34H57N11O8.C2HF3O2/c1-18(2)13-24(31(51)41-22(11-8-12-40-34(38)39)30(50)42-23(28(37)48)16-27(36)47)44-32(52)25(14-19(3)4)45-33(53)26(43-29(49)21(35)17-46)15-20-9-6-5-7-10-20;3-2(4,5)1(6)7/h5-7,9-10,18-19,21-26,46H,8,11-17,35H2,1-4H3,(H2,36,47)(H2,37,48)(H,41,51)(H,42,50)(H,43,49)(H,44,52)(H,45,53)(H4,38,39,40);(H,6,7)/t21-,22-,23-,24-,25-,26-;/m0./s1

InChI key

YICKZNIVMKPQPD-POCCEKOUSA-N

Gene Information

human ... IGF1R(3480)

Application

Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt has been used as a protease-activated receptor 1 (PAR-1) selective activating peptide.

Biochem/physiol Actions

Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt (SFLLRN) acts as a protease-activated receptor 1 (PAR-1) specific agonist peptide.
Thrombin receptor activating peptide (TRAP).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

常规特殊物品

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Certificates of Analysis (COA)

Lot/Batch Number
057M4727V
125M4737V
013M4748V
101M4741V
120M4723V

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M Rijkers et al.
Vox sanguinis, 111(3), 247-256 (2016-10-22)
In mice, loss of sialic acid resulting in shedding of glycoprotein (GP) Ibα and GPV has been linked to platelet survival. The aim of this study was to determine whether loss of sialic acid and the GPIb-IX-V complex contributes to
Thrombin induces Ca2+-dependent glutamate release from RPE cells mediated by PLC/PKC and reverse Na+/Ca2+ exchange
Lopez E, et al.
Molecular Vision (2019)
J. S. Davies
Amino Acids, Peptides and Proteins, 29 (1998)
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Global Trade Item Number

SKUGTIN
S1820-1MG04061836914639