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Merck
CN

SAB1404084

Monoclonal Anti-MSI1, (N-terminal) antibody produced in mouse

clone 1B11, purified immunoglobulin, buffered aqueous solution

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
1B11, monoclonal
Application:
ELISA (c), ELISA (i), IF, IHC (p), WB
Citations:
1
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1B11, monoclonal

form

buffered aqueous solution

mol wt

antigen ~35.57 kDa

species reactivity

human

technique(s)

capture ELISA: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, indirect ELISA: suitable, indirect immunofluorescence: suitable, western blot: 1-5 μg/mL

isotype

IgG2bκ

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MSI1(4440)

General description

This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. (provided by RefSeq)

Immunogen

MSI1 (NP_002433, 1 a.a. ~ 87 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
METDAPQPGL ASPDSPHDPC KMFIGGLSWQ TTQEGLREYF GQFGE VKECL VMRDPLTKRS RGFGFVTFMD QAGVDKVLAQ SRHELDS

Physical form

Solution in phosphate buffered saline, pH 7.4


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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Atsushi Sato et al.
Stem cell research, 12(1), 119-131 (2013-11-05)
Reactive oxygen species (ROS) are involved in various aspects of cancer cell biology, yet their role in cancer stem cells (CSCs) has been poorly understood. In particular, it still remains unclear whether and how ROS control the self-renewal/differentiation process and



Global Trade Item Number

SKUGTIN
SAB1404084-100UG04061829622961