SAB3500889
Monoclonal Anti-ORAI3 antibody produced in mouse
affinity isolated antibody
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
1B4F1, monoclonal
Application:
ELISA
Citations:
5
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
1B4F1, monoclonal
form
buffered aqueous solution
species reactivity
human,
concentration
1 mg/mL
technique(s)
ELISA: suitable, immunoblotting: suitable
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ORAI3(93129)
Immunogen
Antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human ORAI3.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 1 mg/mL in PBS with 0.02% sodim azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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R S Lewis
Annual review of immunology, 19, 497-521 (2001-03-13)
Elevation of intracellular free Ca(2+) is one of the key triggering signals for T-cell activation by antigen. A remarkable variety of Ca(2+) signals in T cells, ranging from infrequent spikes to sustained oscillations and plateaus, derives from the interactions of
Calcium signals mediated by STIM and Orai proteins--a new paradigm in inter-organelle communication.
Jonathan Soboloff et al.
Biochimica et biophysica acta, 1763(11), 1161-1168 (2006-11-07)
In all cells Ca2+ signals are key to controlling a spectrum of cellular responses. Ca2+ signals activated by phospholipase C-coupled receptors have two components-rapid Ca2+ release from ER stores followed by slower Ca2+ entry from outside the cell. The coupling
Jason C Mercer et al.
The Journal of biological chemistry, 281(34), 24979-24990 (2006-06-30)
The molecular nature of store-operated Ca(2+)-selective channels has remained an enigma, due largely to the continued inability to convincingly demonstrate Ca(2+)-selective store-operated currents resulting from exogenous expression of known genes. Recent findings have implicated two proteins, Stim1 and Orai1, as
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB3500889-100UG | 04061832497075 |