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SAB4301137

Sigma-Aldrich

Anti-ACTIN antibody produced in rabbit

affinity isolated antibody

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Synonym(s):
ACTB
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

42 kDa

species reactivity

plant

concentration

1 mg/mL

technique(s)

western blot: 1:500-1:2000 (Cell Lysate)

isotype

IgG

accession no.

NP_190236.1

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

Arabidopsis thaliana ... ACT12(823805)

General description

Actin/ actin β(ACTB) is encoded by the gene mapped to human chromosome 7p15-p12. In mammals, actin protein consists of six different isoforms encoded by separate genes. The four isoforms αskeletal-actin, αcardiac-actin, αsmooth-actin, and γ smooth-actin are expressed in skeletal, cardiac and smooth muscle. The other two isoforms, β cyto-actin and γ cyto-actin are ubiquitously expressed.

Specificity

The antibody detects endogenous levels of total ACTIN protein.

Immunogen

Synthetic peptide corresponding to residues near the N terminal of Arabidopsis thaliana actin

Biochem/physiol Actions

Actin plays a vital role in various cellular processes, such as cell division, migration, junction formation, chromatin remodeling, transcriptional regulation, vesicle trafficking, and cell shape regulation. Polymorphism in the smooth muscle α-actin (ACTA2) is associated with the development of thoracic aortic aneurysms and dissections.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

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