SAB4502065
Anti-PAK1 antibody produced in rabbit
affinity isolated antibody
Synonym(s):
α-PAK, PAK-1, Serine/threonine-protein kinase PAK 1, p21-activated kinase 1, p65-PAK
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, IHC, WB
Citations:
3
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 60 kDa
species reactivity
rat, mouse, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000, immunofluorescence: 1:100-1:500, immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... PAK1(5058)
General description
Anti-PAK1 Antibody detects endogenous levels of total PAK1 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human PAK1/2.
Immunogen Range: 165-214
Immunogen Range: 165-214
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Juan Han et al.
BMC cancer, 14, 650-650 (2014-09-04)
P21-activated protein kinase 1 (PAK1), a main downstream effector of small Rho GTPases, is overexpressed in many malignancies. PAK1 overexpression is associated with poor prognosis in some tumor types, including breast cancer, gastric cancer, and colorectal cancer. However, the expression
Zhenxing Wei et al.
Cancer cell international, 20, 82-82 (2020-03-20)
Tongue squamous cell carcinoma (TSCC) is the most common oral malignancy. Previous studies found that microRNA (miR)-26a and miR-26b were downregulated in TSCC tissues. The current study was designed to explore the effects of miR-26a/miR-26b on TSCC progression and the
Cheng-Kang Chiang et al.
PLoS genetics, 10(10), e1004695-e1004695 (2014-10-21)
The suprachiasmatic nucleus (SCN) acts as the central clock to coordinate circadian oscillations in mammalian behavior, physiology and gene expression. Despite our knowledge of the circadian transcriptome of the SCN, how it impacts genome-wide protein expression is not well understood.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB4502065-100UG | 04061835714605 |