Anti-p53 antibody produced in rabbit

Anti-p53 Antibody detects endogenous levels of total p53 protein.

TP53 gene is mapped to human chromosome 17p13.1.

The antiserum was produced against synthesized peptide derived from human p53.

Immunogen Range: 344-393

TP53 gene is involved in the regulation of cell cycle, senescence and apoptosis upon oncogene activation, stress and DNA damage. Therefore, the gene has anti-tumor activity initiation and prevents tumor progression. Mutation in TP53 is known to be the major cause of almost half of all human malignancy. Breast cancer is one such condition in which, the disease development is severe due to mutation in TP53 gene.

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Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.