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SAB4503446

Anti-CBL antibody produced in rabbit

affinity isolated antibody

Synonym(s):

CBL E3 ubiquitin protein ligase, CBL2, Cas-Br-M (murine) ecotropic retroviral transforming, Proto-oncogene c-CBL, Signal transduction protein CBL

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD01633067
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IHC, WB
Citations:
2
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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 99 kDa

species reactivity

human, mouse, rat

concentration

~1 mg/mL

technique(s)

ELISA: 1:5000, immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000

NCBI accession no.

P22681

UniProt accession no.

P22681

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CBL(867)

General description

Anti-CBL Antibody detects endogenous levels of total CBL protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human CBL.

Immunogen Range: 640-689

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品

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Certificates of Analysis (COA)

Lot/Batch Number
210467

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Kristina Brand et al.
Human mutation, 35(11), 1372-1381 (2014-09-03)
Noonan syndrome, a congenital disorder comprising a characteristic face, short stature, heart defects, learning difficulties, and a predisposition to malignancies, is caused by heterozygous germline mutations in genes encoding components of RAS-MAPK signaling pathways. Mutations in the CBL tumor suppressor
Lasse Boding et al.
European journal of immunology, 44(10), 3109-3118 (2014-07-22)
Midline 1 (MID1) is a microtubule-associated ubiquitin ligase that regulates protein phosphatase 2A activity. Loss-of-function mutations in MID1 lead to the X-linked Opitz G/BBB syndrome characterized by defective midline development during embryogenesis. Here, we show that MID1 is strongly upregulated

Global Trade Item Number

SKUGTIN
SAB4503446-100UG04061835727483