SAB4504299
Anti-phospho-Casein Kinase II α (pTyr255) antibody produced in rabbit
affinity isolated antibody
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About This Item
NACRES:
NA.43
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
5
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 45 kDa
species reactivity
human, mouse, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:10000, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pTyr255)
Gene Information
human ... CSNK2A1(1457)
General description
Casein kinase II α(CK2) is a pleiotropic serine/threonine kinase, that is located on human chromosome 16p13. 2-p13. 3.
Immunogen
The antiserum was produced against synthesized peptide derived from human Casein Kinase II alpha around the phosphorylation site of Tyr255.
Immunogen Range: 221-270
Immunogen Range: 221-270
Biochem/physiol Actions
Casein kinase II α(CK2) regulates T-cell polarization by initiating the activation of dendritic cells. CK2 participates in the development of breast carcinoma. Mutations in CK2 results in neurodevelopmental abnormalities and dysmorphic features. This protein induces prosurvival and proinflammatory signaling pathways.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
低风险生物材料
常规特殊物品
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Assignment of the human casein kinase II [alpha][prime] subunit gene (CSNK2A1) to chromosome 16p13. 2-p13. 3
Yang-Feng TL, et al.
Genomics, 19(1) (1994)
De novo mutations in CSNK2A1 are associated with neurodevelopmental abnormalities and dysmorphic features
Okur V, et al.
Human Genetics, 135(7), 699-705 (2016)
CK2?/CSNK2A1 Phosphorylates SIRT6 and Is Involved in the Progression of Breast Carcinoma and Predicts Shorter Survival of Diagnosed Patients
Bae JS, et al.
The American Journal of Pathology, 186(12), 3297-3315 (2016)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB4504299-100UG | 04061832524931 |