SAB4700750
Monoclonal Anti-CD117 antibody produced in mouse
clone 104D2, purified immunoglobulin, buffered aqueous solution
Synonym(s):
Anti-c-Kit
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Technique(s):
immunocytochemistry: suitable, immunohistochemistry: suitable, flow cytometry: suitable, immunoprecipitation (IP): suitable
Conjugate:
unconjugated
Application:
FACS, ICC, IHC, IP
Citations:
7
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
104D2, monoclonal
form
buffered aqueous solution
species reactivity
bovine, nonhuman primates, human
concentration
1 mg/mL
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, flow cytometry: suitable, immunoprecipitation (IP): suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... KIT(3815)
General description
The mouse monoclonal antibody 104D2 detects extracellular part of CD117 / c-Kit protooncogen.
HLDA VI; WS Code C-30.
HLDA VI; WS Code C-30.
Immunogen
MOLM-1 megakaryocytic cells
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Weina Zhang et al.
Frontiers of medicine, 13(3), 388-397 (2018-09-13)
Collaboration of c-KIT mutations with AML1-ETO (AE) has been demonstrated to induce t(8; 21) acute myeloid leukemia (AML). Targeted therapies designed to eliminate AE and c-KIT oncoproteins may facilitate effective treatment of t(8; 21) AML. Homoharringtonine (HHT) features activity against
Bao Yang et al.
Oncology letters, 14(3), 3825-3831 (2017-09-21)
Myeloid sarcoma (MS) is a localized tumor composed of premature precursors of granulocytic cells, which may occur in any organ and most commonly involves the soft tissue and musculoskeletal system. This malignancy may occur in the presence or absence of
Francesco Ciccia et al.
Rheumatology (Oxford, England), 53(7), 1313-1320 (2014-03-08)
The aim of this study was to evaluate the role of rituximab (RTX) in modulating the expression of the IL-17/IL-23 pathway in the salivary glands (SGs) of patients with primary SS (pSS). Consecutive SG biopsies were obtained from 15 patients
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB4700750-100UG | 04061832716923 |