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Merck
CN

SAB5300249

Monoclonal Anti-MLH1 antibody produced in mouse

clone 4C9C7, ascites fluid

Synonym(s):

COCA2, FCC2, HNPCC

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
4C9C7, monoclonal
Application:
ELISA (d), IF, IHC, WB
Citations:
7
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

4C9C7, monoclonal

mol wt

85 kDa

species reactivity

human, monkey

technique(s)

direct ELISA: 1:10,000, immunohistochemistry: 1:200-1:1,000, indirect immunofluorescence: 1:200-1:1,000, western blot: 1:500-1:2,000

isotype

IgG1

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MLH1(4292)

Immunogen

Purified recombinant fragment of MLH1 (aa381-483) expressed in E.coli.
Mouse monoclonal antibody raised against MLH1

Physical form

Ascitic fluid containing 0.03% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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M Tanyi et al.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 40(11), 1445-1452 (2014-08-12)
Hereditary Non-Polyposis Colorectal Cancer is an inherited disease with deleterious germline mutations in the DNA mismatch repair genes causing the development of colon cancer and other malignancies. This is the first study in Hungary screening the population of our colorectal
Michael S Landau et al.
Human pathology, 45(8), 1704-1712 (2014-06-09)
Reduced CDX2 and cytokeratin 20 (CK20) expression in colorectal carcinoma with BRAF mutation and high-level microsatellite instability (MSI-H) has been well documented. The immunophenotype of BRAF-mutated microsatellite stable (MSS) colorectal carcinoma has not been reported. We analyzed 205 colorectal carcinomas
Koah R Vierkoetter et al.
Gynecologic oncology, 135(1), 81-84 (2014-08-06)
Patients with Lynch Syndrome are at an increased risk for a variety of malignancies, including ovarian cancer. Ovarian cancers associated with Lynch Syndrome are predominantly clear cell or endometrioid in histology. Lynch Syndrome is characterized by germline mutations in mismatch



Global Trade Item Number

SKUGTIN
SAB5300249-100UL04061837599309