SAB5300293
Monoclonal Anti-GAB1 antibody produced in mouse
clone 1A7, purified immunoglobulin, buffered aqueous solution
Synonym(s):
N/A
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
1A7, monoclonal
Application:
ELISA (d), FACS, IHC, WB
Citations:
2
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
1A7, monoclonal
form
buffered aqueous solution
mol wt
76.6 kDa
species reactivity
human
technique(s)
direct ELISA: 1:10,000, flow cytometry: 1:200-1:400, immunohistochemistry: 1:200-1:1,000, western blot: 1:500-1:2,000
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... GAB1(2549)
Immunogen
Purified recombinant fragment of human GAB1 expressed in E.coli.
Mouse monoclonal antibody raised against GAB1
Mouse monoclonal antibody raised against GAB1
Physical form
Purified antibody in PBS with 0.05% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Hui Liu et al.
Medical oncology (Northwood, London, England), 31(8), 77-77 (2014-07-08)
Grb2-associated binder 1 (Gab1) and Gab2 play important roles in cancer cell signaling. In particular, it has been demonstrated that the upregulation of Gab2 may be correlated with the World Health Organization (WHO) grade of gliomas and that patients with
Selma Pennacchietti et al.
Cancer research, 74(22), 6598-6609 (2014-09-14)
Cell-based drug screenings indicate that tumors displaying c-MET gene amplification are "addicted" to MET signaling and therefore are very sensitive to MET-targeted agents. However, these screenings were conducted in the absence of the MET ligand, hepatocyte growth factor (HGF), which
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB5300293-100UG | 04061837599729 |