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SAB5700836

Anti-KU70 antibody produced in rabbit

Name: Anti-KU70 antibody produced in rabbit
Brand: SIGMA

Synonym(s):

CTC75, CTCBF, G22P1, KU70, ML8, TLAA, XRCC6

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IF, IHC, IP, WB

Citations:

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Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

65, 69

species reactivity

rat, human, mouse

concentration

5.86 mg/ml

technique(s)

immunofluorescence: 1:50-1:100, immunohistochemistry: 1:50-1:100, immunoprecipitation (IP): 1:20-1:50, western blot: 1:500-1:2000

UniProt accession no.

P12956

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... XRCC6(2547)

Description

General description

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 408-609 of human KU70 (NP_001460.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c