SAB5702282
Anti-SOCS1 Antibody, clone 5T6Z10, Rabbit Monoclonal
Synonym(s):
SOCS1,CIS1,CISH1,JAB,SOCS-1,SSI-1,SSI1,TIP3,TIP-3
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
5T6Z10, monoclonal
Application:
IF, IHC
Citations:
-
biological source
rabbit
Quality Level
conjugate
unconjugated
material
colorless
clone
5T6Z10, monoclonal
form
liquid
species reactivity
human, rat
concentration
1 mg/mL
technique(s)
immunofluorescence: 1:50 - 1:200, immunohistochemistry: 1:50 - 1:200
color
colorless
isotype
IgG
immunogen sequence
MVAHNQVAADNAVSTAAEPRRRPEPSSSSSSSPAAPARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRAEPVGT
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SOCS1(8651)
General description
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SOCS1 (NP_003736.1).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Application
IHC, IF/ICC
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Skin Sens. 1
Storage Class
10 - Combustible liquids
wgk
WGK 3
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB5702282-100UL | 04065270699640 |