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Merck
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SAB5702849

Anti-LEF1 Antibody, clone 9I9T4, Rabbit Monoclonal

Synonym(s):

LEF-1, TCF10, TCF1ALPHA, TCF7L3

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
9I9T4, monoclonal
Application:
IF, IHC, WB
Citations:
-
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biological source

rabbit

Quality Level

conjugate

unconjugated

material

colorless

clone

9I9T4, monoclonal

form

liquid

mol wt

30-50 kDa

species reactivity

mouse

concentration

0.28 mg/mL

technique(s)

immunofluorescence: 1:100 - 1:500, immunohistochemistry: 1:500 - 1:900, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

LADIKSSLVNESEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHA

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... LEF1(51176)

General description

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human LEF1 (Q9UJU2).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC, IF/ICC


Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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Global Trade Item Number

SKUGTIN
SAB5702849-100UL04065270689283