SAB5702891
Anti-NEDD4L Antibody, clone 3W9J2, Rabbit Monoclonal
Synonym(s):
NEDD4-2, NEDD4.2, PVNH7, RSP5, hNEDD4-2
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
3W9J2, monoclonal
Application:
WB
Citations:
-
biological source
rabbit
Quality Level
conjugate
unconjugated
material
colorless
clone
3W9J2, monoclonal
form
liquid
mol wt
135 kDa
species reactivity
human
concentration
0.75 mg/mL
technique(s)
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
NHPVIQWFWKAVLLMDAEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQLFTIEQWGSPEKLPRAHTCFNRLDLPPYETFEDLREKLLMAVENAQGFEGVD
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... NEDD4L(23327)
General description
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 876-975 of human NEDD4L (Q96PU5).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB5702891-100UL | 04065270707178 |