T0910
Thioredoxin from Escherichia coli
recombinant, expressed in E. coli, essentially salt-free, lyophilized powder, ≥3 units/mg protein
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Form:
essentially salt-free, lyophilized powder
Assay:
≥90% (SDS-PAGE)
Biological source:
Escherichia coli
Recombinant:
expressed in E. coli
Mol wt:
11.7 kDa
biological source
Escherichia coli
Quality Level
recombinant
expressed in E. coli
assay
≥90% (SDS-PAGE)
form
essentially salt-free, lyophilized powder
specific activity
≥3 units/mg protein
mol wt
11.7 kDa
technique(s)
activity assay: suitable
solubility
water: 1.90-2.10 mg/mL, clear, colorless
Protein ID accession no.
UniProt accession no.
application(s)
cell analysis
storage temp.
−20°C
Gene Information
Escherichia coli K12 ... trxA(948289)
General description
Research area: Cell Signaling
Thioredoxin from Escherichia coli is a monomeric, globular protein. It has a central β-sheet surrounded by α-helices.
Thioredoxin from Escherichia coli is a monomeric, globular protein. It has a central β-sheet surrounded by α-helices.
Application
Thioredoxin from Escherichia coli has been used in thioredoxin reductase assay, peroxidase-coupled thioredoxin system assay and peroxiredoxin assay. It has also been used to study its effects on photoreceptor death in a mouse model of retinitis pigmentosa (RP) and its potential to modify retinal oxidative stress, glial changes, and vascular changes during the progression of the disease.
Biochem/physiol Actions
Thioredoxin from Escherichia coli catalyzes REDOX reactions and has a role in various biological processes. It modulates the structure and activity of many proteins. The enzyme thioredoxin reductase catalyzes the reduction of thioredoxin. Thioredoxin also has a role in oxidative stress response.Thioredoxin, known as both adult T cell leukemia-derived factor (ADF) and a cellular redox enzyme, functions as a cytokine or chemokine, facilitating cell-to-cell communication. Additionally, it plays a role in regulating cell growth and apoptosis.
Mediates the reduction of disulfide bonds in proteins.
Other Notes
GenBank® Accession Number M26133.
One unit will cause a ΔA650 of 1.0 in 1 min at 25 °C in the insulin reduction assay.
Legal Information
GenBank is a registered trademark of United States Department of Health and Human Services
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
常规特殊物品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Related Content
Thioredoxin from Escherichia coli as a Role Model of Molecular Recognition, Folding, Dynamics and Function.
Vazquez DS
Protein and peptide letters, 22(9), 801-815 (2015)
Proteomic analysis of thioredoxin-targeted proteins in Escherichia coli.
Kumar JK
Proceedings of the National Academy of Sciences of the USA, 101(11), 3759-3764 (2004)
Mechanism and structure of thioredoxin reductase from Escherichia coli.
Williams CH Jr
Faseb Journal, 9(13), 1267-1276 (1995)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| T0910-1MG | 04061837336140 |