T7004
Thymidine 5′-monophosphate disodium salt hydrate
≥99%
Synonym(s):
5′-Thymidylic acid disodium salt, TMP, dTMP
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About This Item
Empirical Formula (Hill Notation):
C10H13N2Na2O8P · xH2O
CAS Number:
Molecular Weight:
366.17 (anhydrous basis)
UNSPSC Code:
41106305
NACRES:
NA.51
PubChem Substance ID:
EC Number:
251-518-0
Beilstein/REAXYS Number:
4086927
MDL number:
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
H2O: 100 mg/mL to clear, colorless
Storage temp.:
−20°C
biological source
synthetic (organic)
Quality Level
assay
≥99%
form
powder
solubility
H2O: 100 mg/mL to clear, colorless
storage temp.
−20°C
SMILES string
O.[Na+].[Na+].CC1=CN([C@H]2C[C@H](O)[C@@H](COP([O-])([O-])=O)O2)C(=O)NC1=O
InChI
1S/C10H15N2O8P.2Na.H2O/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18;;;/h3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18);;;1H2/q;2*+1;/p-2/t6-,7+,8+;;;/m0.../s1
InChI key
KCOPAVKVHIWPKB-SPSULGLQSA-L
General description
Thymidine 5′-monophosphate de novo synthesis from deoxyuridine monophosphate (dUMP) is catalyzed by the enzyme thymidylate synthase.
Application
Thymidine 5′-monophosphate disodium salt hydrate has been used as a standard for the quantification of metabolites from plasma and tumor interstitial fluid using liquid chromatography-mass spectrometry analysis (LC/MS). It has also been used as a single deoxy-mononucleotide to test its effect on the cell growth of human malignant intestinal CaCo-2 cells and normal rat intestinal cell line IEC-6 cells.
Thymidine 5′-monophosphate disodium salt hydrate has been used as a standard solution.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Medical Biochemistry null
Global Trade Item Number
| SKU | GTIN |
|---|---|
| T7004-100MG | 04061833265765 |
| T7004-1G | 04061837372186 |
| T7004-250MG | 04061833265772 |