T7254
Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride
powder, ≥96% (TLC)
Synonym(s):
(3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride, (3S)-7-Amino-1-chloro-3-tosylamino-2-heptanone hydrochloride, TLCK, Tosyl-L-lysyl-chloromethane hydrochloride
Select a Size
About This Item
Product Name
Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride, ≥96% (TLC), powder
biological source
synthetic (organic)
Quality Level
assay
≥96% (TLC)
form
powder
potency
10-100 μM effective concentration
solubility
H2O: 50 mg/mL
storage temp.
−20°C
SMILES string
Cl[H].Cc1ccc(cc1)S(=O)(=O)N[C@@H](CCCCN)C(=O)CCl
InChI
1S/C14H21ClN2O3S.ClH/c1-11-5-7-12(8-6-11)21(19,20)17-13(14(18)10-15)4-2-3-9-16;/h5-8,13,17H,2-4,9-10,16H2,1H3;1H/t13-;/m0./s1
InChI key
YFCUZWYIPBUQBD-ZOWNYOTGSA-N
Gene Information
human ... NFKB1(4790), NFKB2(4791)
Application
- in chymotrypsin purification to prevent binding of trypsins to the affinity support by inhibiting them in the crude extract
- as a protease inhibitor in tissue and cell homogenization
- as a trypsin inhibitor to determine the specific protease activity levels
Biochem/physiol Actions
Packaging
Disclaimer
Still not finding the right product?
Explore all of our products under Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1B
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Protocols
凝血酶是一种内溶性丝氨酸蛋白酶，可选择性裂解纤维蛋白原的精氨酸-甘氨酸键，从而形成纤维蛋白并释放纤维蛋白肽A和B。
Thrombin is an endolytic serine protease that selectively cleaves the Arg–Gly bonds of fibrinogen to form fibrin and release fibrinopeptides A and B.