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Merck
CN

U116

U-99194 maleate salt

≥98% (HPLC), solid

Synonym(s):

5,6-Dimethoxy-2-(di-n-propylamino)indan maleate salt

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About This Item

Empirical Formula (Hill Notation):
C17H27NO2 · C4H4O4
CAS Number:
Molecular Weight:
393.47
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
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Quality Level

assay

≥98% (HPLC)

form

solid

color

white

solubility

H2O: >5 mg/mL

SMILES string

OC(=O)\C=C/C(O)=O.CCCN(CCC)C1Cc2cc(OC)c(OC)cc2C1

InChI

1S/C17H27NO2.C4H4O4/c1-5-7-18(8-6-2)15-9-13-11-16(19-3)17(20-4)12-14(13)10-15;5-3(6)1-2-4(7)8/h11-12,15H,5-10H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

FSIQDESGRQTFNN-BTJKTKAUSA-N

Gene Information

human ... DRD3(1814)

Application

U-99194 maleate has been used as a dopaminergic antagonist to study its effects on immobility episodes and yawning frequency in rats.

Biochem/physiol Actions

U-99194 is a putative D3 antagonist with a 30-fold preference for the dopamine D3 vs. D2 receptor.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Preparation Note

U-99194 maleate salt is soluble in water at a concentration >5 mg/ml.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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