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WH0009223M3

Monoclonal Anti-MAGI1 antibody produced in mouse

Name: Monoclonal Anti-MAGI1 antibody produced in mouse
Brand: SIGMA

clone 7B4, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-AIP3, Anti-BAIAP1, Anti-BAP1, Anti-MAGI1, Anti-TNRC19, Anti-WWP3, Anti-membrane associated guanylate kinase, WW and PDZ domain containing 1

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD04040441

Conjugate:

unconjugated

Clone:

7B4, monoclonal

Application:

ELISA (i), IF, WB

Citations:

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Properties

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

7B4, monoclonal

form

buffered aqueous solution

species reactivity

mouse, human, rat

technique(s)

indirect ELISA: suitable, indirect immunofluorescence: suitable, western blot: 1-5 μg/mL

isotype

IgG1κ

GenBank accession no.

NM_004742

UniProt accession no.

Q96QZ7

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MAGI1(9223)

Description

Immunogen

MAGI1 (NP_004733, 761 a.a. ~ 859 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
SHSTQVLPEFPPAEAQAPDQTDSSGQKKPDPFKIWAQSRSMYENRPMSPSPASGLSKGEREREINSTNFGECPIPDYQEQDIFLWRKETGFGFRILGGN

Application

Monoclonal Anti-MAGI1 antibody produced in mouse has been used for Western Blotting.

Biochem/physiol Actions

Membrane associated guanylate kinase, WW and PDZ domain containing 1 (MAGI1) acts as a scaffolding protein. It takes part in tight junction formation and binds to β-catenin to suppress the Wnt signaling pathway. The gene encoding it has been linked with schizophrenia and the protein is downregulated in hepatocellular carcinoma.

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

常规特殊物品

低风险生物材料

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21942217

Derringer J

JAMA Psychiatry (Chicago, Ill.), 72(7), 642-650 (2015)

Downregulation of MAGI1 associates with poor prognosis of hepatocellular carcinoma.

Zhang G, et.al

Journal of Investigative Surgery, 25(2), 93-99 (2012)

AmotL2 integrates polarity and junctional cues to modulate cell shape

Sara Hultin

Scientific Reports, 7 (2017)

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Global Trade Item Number

SKU	GTIN
WH0009223M3-100UG	04061831649789