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Merck
CN

PHL89612

Cryptotanshinone

phyproof® Reference Substance

Synonym(s):

(R)-(−)-1,6,6-Trimethyl-1,2,6,7,8,9-hexahydrophenanthro[1,2-b]furan-10,11-dione, Tanshinone C

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About This Item

Empirical Formula (Hill Notation):
C19H20O3
CAS Number:
Molecular Weight:
296.36
NACRES:
NA.24
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
5445400
MDL number:
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grade

primary reference standard

product line

phyproof® Reference Substance

assay

≥90.0% (HPLC)

form

solid

manufacturer/tradename

PhytoLab

SMILES string

C[C@H]1COC2=C1C(=O)C(=O)c3c4CCCC(C)(C)c4ccc23

InChI

1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1

InChI key

GVKKJJOMQCNPGB-JTQLQIEISA-N

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Cryptotanshinone is an antibacterial and anti-inflammatory compound originally extracted from the roots of Salvia miltiorrhiaz (danshen). Cryptotanshinone has been found to inhibit HIF activation and to inhibit macrophage migration negatively regulate the PI3K pathway. It has demonstrated activity against several strains of Staphylococcus aureus.

Other Notes

This compound is commonly found in plants of the genus: salvia

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG


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Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
225371-100G04061838779441
36572-250MG04061833947074