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1337809

USP

Imipenem monohydrate

Name: Imipenem monohydrate
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

(5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monohydrate, Primaxin monohydrate, Tienam monohydrate

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About This Item

Empirical Formula (Hill Notation):

C₁₂H₁₇N₃O₄S · H₂O

CAS Number:

74431-23-5

Molecular Weight:

317.36

NACRES:

NA.24

PubChem Substance ID:

329750155

UNSPSC Code:

41116107

MDL number:

MFCD09753321

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Properties

grade

pharmaceutical primary standard

API family

imipenem

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

O.C[C@@H](O)[C@@H]1[C@H]2CC(SCCNC=N)=C(N2C1=O)C(O)=O

InChI

1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1

InChI key

GSOSVVULSKVSLQ-JJVRHELESA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Imipenem monohydrate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Imipenem
Imipenem and Cilastatin for Injectable Suspension
Imipenem and Cilastatin for Injection

Biochem/physiol Actions

Imipenem monohydrate is a broad spectrum B-lactam antibiotic.

Imipenem monohydrate is a broad spectrum B-lactam antibiotic. It is a member of the carbapenem class of "magic bullet" antibiotics for severe infections.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品

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Imipenem heteroresistance: high prevalence among Enterobacteriaceae Klebsiella pneumoniae carbapenemase producers.

Carolina Silva Nodari et al.

Journal of medical microbiology, 64(Pt 1), 124-126 (2014-10-30)

Risk factors and outcome analysis of acinetobacter baumannii complex bacteremia in critical patients.

Hao-Yuan Lee et al.

Critical care medicine, 42(5), 1081-1088 (2014-01-08)

Acinetobacter baumannii complex bacteremia has been identified increasingly in critical patients admitted in ICUs. Notably, A. baumannii complex bacteremia has a high mortality rate, yet the risk factors associated with mortality remain unclear and controversial. Retrospective study. All adult ICUs

The deadly impact of extreme drug resistance in Acinetobacter baumannii.

Brad Spellberg et al.

Critical care medicine, 42(5), 1289-1291 (2014-04-17)

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Global Trade Item Number

SKU	GTIN
1337809-100MG	04061835345502