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149837

2-乙氧基-1-乙氧羰基-1,2-二氢喹啉

Name: 2-乙氧基-1-乙氧羰基-1,2-二氢喹啉
Brand: ALDRICH

≥99%, for peptide synthesis

别名:

2-乙氧基-1,2-二氢-1-喹啉羧酸乙酯, N-乙氧羰基-2-乙氧基-1,2-二氢喹啉, EEDQ

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关于此项目

经验公式（希尔记法）:

C₁₄H₁₇NO₃

化学文摘社编号:

16357-59-8

分子量:

247.29

NACRES:

NA.22

PubChem Substance ID:

24848976

UNSPSC Code:

12352005

EC Number:

240-418-2

MDL number:

MFCD00006703

Beilstein/REAXYS Number:

533048

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属性

产品名称

2-乙氧基-1-乙氧羰基-1,2-二氢喹啉, ≥99%

Quality Level

200

assay

≥99%

form

solid

reaction suitability

reaction type: Coupling Reactions

mp

62-67 °C (lit.)

application(s)

peptide synthesis

functional group

ether

storage temp.

2-8°C

SMILES string

CCOC1C=Cc2ccccc2N1C(=O)OCC

InChI

1S/C14H17NO3/c1-3-17-13-10-9-11-7-5-6-8-12(11)15(13)14(16)18-4-2/h5-10,13H,3-4H2,1-2H3

InChI key

GKQLYSROISKDLL-UHFFFAOYSA-N

说明

General description

2-乙氧基-1-乙氧羰基-1,2-二氢喹啉(EEDQ)是稳定试剂，可用于高产率制备酰胺和多肽。本品提供现成货品。室温下，可溶于含有机溶剂的水性介质，但不溶于水。用作肽合成偶联剂。

Application

2-乙氧基-1-乙氧羰基-1,2-二氢喹啉用作偶联剂：

用于壳聚糖及其两亲性衍生物的区域选择性季铵化。
用于制备酰胺型S-MA（扁桃酸）衍生物修饰的石英晶体微天平(QCM)传感器。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Temperature-modulated cell-separation column using temperature-responsive cationic copolymer hydrogel-modified silica beads.

Kenichi Nagase et al.

Colloids and surfaces. B, Biointerfaces, 178, 253-262 (2019-03-16)

There is strong demand for cell separation methods that do not decrease cell activity or modify cell surfaces. Here, new temperature-modulated cell-separation columns not requiring cell-surface premodification are described. The columns were packed with temperature-responsive cationic polymer hydrogel-modified silica beads.

Brain alpha(2)-adrenoceptors in monoamine-depleted rats: increased receptor density, G coupling proteins, receptor turnover and receptor mRNA.

C Ribas et al.

British journal of pharmacology, 132(7), 1467-1476 (2001-03-27)

1. This study was designed to assess the molecular and cellular events involved in the up-regulation (and receptor supersensitivity) of brain alpha(2)-adrenoceptors as a result of chronic depletion of noradrenaline (and other monoamines) by reserpine. 2. Chronic reserpine (0.25 mg

Differential effects of N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) on various 5-HT receptor binding sites in the rat brain.

H Gozlan et al.

Neuropharmacology, 33(3-4), 423-431 (1994-03-01)

The effects of N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ), an alkylating agent producing irreversible blockade of various membrane bound receptors in brain, were investigated on four different types of serotonin receptors, 5-HT1A, 5-HT1B, 5-HT2A and 5-HT3, in various brain regions in the rat. In

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货号	GTIN
149837-5G	04061838738479
149837-100G	04061838346131
149837-25G	04061838738462