Quality Level
form
amorphous
feed ratio
lactide:glycolide 50:50
degradation timeframe
<3 months
viscosity
0.16-0.24 dL/g
transition temp
Tg 42-46 °C
storage temp.
2-8°C
SMILES string
O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O
InChI
1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2
InChI key
LCSKNASZPVZHEG-UHFFFAOYSA-N
Application
聚((D,L-丙交酯-co-乙交酯)(PLGA)可用于:
- 为H2S供体配制非水药物递送系统,以促进药物的持续释放。
- 制备含有分散于 PLGA–PEG–PLGA聚合物凝胶中的更昔洛韦微球的聚合物混合物。该制剂可用作更昔洛韦药物的持续给药系统。
Legal Information
Evonik产品
RESOMER is a registered trademark of Evonik Rohm GmbH
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
商品
商业生物材料已停滞不前超过30年的时间,因为很少有材料能够成功地从实验台过渡到临床使用。合成型脂族聚酯因其悠久的历史和获得美国食品药品监督管理局(FDA)批准的记录,一直在可吸收生物材料领域占据主导地位。
In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.
Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.
Diazeniumdiolate-doped poly (lactic-co-glycolic acid)-based nitric oxide releasing films as antibiofilm coatings.
Cai W,et al.
Biomaterials, 33(32), 7933-7944 (2012)
Z Zhuang et al.
Journal of dental research, 98(2), 200-208 (2018-11-06)
Periodontitis is characterized by the progressive destruction of tooth-supporting alveolar bone, which is mainly caused by chronic inflammation in response to persistent bacterial insult. It has recently become clear that the pathogenesis of periodontitis is associated with a high ratio
Rongcai Liang et al.
International journal of pharmaceutics, 454(1), 344-353 (2013-07-23)
Peptide or protein degradation often occurs when water flows into the dosage form. The aim of this study was to investigate the effect of water on exenatide acylation in poly(lactide-co-glycolide) (PLGA) microspheres. Exenatide-loaded PLGA microspheres were incubated at different relative
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 719897-5G | 04061835563708 |
| 719897-1G | 04061832855455 |