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Merck
CN

765260

NH2 功能化金纳米颗粒

5 nm diameter, amine functionalized, PEG 3000 coated, OD 50, dispersion in H2O

别名:

Au NP NH2, 金胶体

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关于此项目

NACRES:
NA.23
UNSPSC Code:
12162002
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material

PEG 3000

Quality Level

form

dispersion in H2O, nanoparticles

packaging

glass bottle of 1 mL

OD

50

diameter

5 nm

pH

6.0-8.0 (25 °C)

solubility

water: miscible

density

1.00 g/cm3

λmax

515 nm

functional group

amine

storage temp.

2-8°C

Application

Amine functionalized, PEG 3000 coated, OD 50, and H2O dispersed gold nanoparticles (5 nm) can be used in the activation of silica nanosphere for the decomposition of formic acid. They may be used in the radiosensitization and imaging of cancer cells.
AuNPs can be potentially immobilized on antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. They can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization, which can be used in the diagnosis of COVID-19.
功能化颗粒已广泛用于研究纳米颗粒的细胞摄取和靶向药物递送。

Features and Benefits

  • Negatively charged siRNA-PEG complex which is attached to positively charged GNPs is easily cleavable in reductive cytosolic environment thus enabling the release of siRNA into cytosol.
  • Decreases the cytotoxicity and increases efficiency of GNPs. PEG increases the stability of the nanoparticles and prevents agglomeration.


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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

最近出现的许多高功能纳米材料为癌症的认识、诊断和治疗提供了新的方案。

Biomaterials science integrates smart materials into biological research, requiring a deep understanding of biological systems.

The recent emergence of a number of highly functional nanomaterials has enabled new approaches to the understanding, diagnosis, and treatment of cancer.


Scott H Brewer et al.
Langmuir : the ACS journal of surfaces and colloids, 21(20), 9303-9307 (2005-09-21)
The interaction of bovine serum albumin (BSA) with gold colloids and surfaces was studied using zeta-potential and quartz crystal microbalance (QCM) measurements, respectively, to determine the surface charge and coverage. The combination of these two measurements suggests that BSA binding
Functionalized gold nanoparticles and their biomedical applications
Tiwari, P. M., Vig, K., Dennis, V. A., & Singh, S. R.
Nanomaterials, 1(1), 31-63 (2011)



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货号GTIN
765260-1ML04061837523441