A4926
1,2-双（2-氨基苯氧基）乙烷- N, N, N′, N′-四乙酸
98%
别名:
2,2′-(亚乙二氧基)双苯胺-N,N,N′,N′-四乙酸, BAPTA, 亚乙二氧基双(邻亚苯基次氮基)四乙酸
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关于此项目
经验公式（希尔记法）:
C22H24N2O10
化学文摘社编号:
分子量:
476.43
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5192406
Quality Level
assay
98%
form
powder
density
±1.494 g/cm3 at 25 °C (Predicted)
storage temp.
2-8°C
SMILES string
OC(=O)CN(CC(O)=O)c1ccccc1OCCOc2ccccc2N(CC(O)=O)CC(O)=O
InChI
1S/C22H24N2O10/c25-19(26)11-23(12-20(27)28)15-5-1-3-7-17(15)33-9-10-34-18-8-4-2-6-16(18)24(13-21(29)30)14-22(31)32/h1-8H,9-14H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32)
InChI key
FTEDXVNDVHYDQW-UHFFFAOYSA-N
General description
在自然界 1,2-双（2-氨基苯氧基）乙烷-N,N,N',N'四乙酸 (BAPTA) 是大鼠脑缺血神经保护剂 BAPTA-AM (BAPTA-tetra (actoxymethyl ester)) 的主要代谢产物。BAPTA 是一种细胞间 Ca 2 + 螯合剂。
Application
The product can be used in various R&D applications such as:
Neuroscience: Used to suppress intracellular Ca2+ overload, reduce neuronal apoptosis, and preserve electrophysiological function in injury models, demonstrating strong neuroprotective action.
Pharmacology: Enables precise buffering of intracellular Ca2+ levels, allowing researchers to distinguish Ca2+‑ dependent drug effects and dissect therapeutic signaling mechanisms.
Neuroscience: Used to suppress intracellular Ca2+ overload, reduce neuronal apoptosis, and preserve electrophysiological function in injury models, demonstrating strong neuroprotective action.
Pharmacology: Enables precise buffering of intracellular Ca2+ levels, allowing researchers to distinguish Ca2+‑ dependent drug effects and dissect therapeutic signaling mechanisms.
Other Notes
pKa: 1.401 ± 0.10 (predicted)
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
商品
一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.