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D9754

2-氨乙基二苯基硼酸盐

97%

别名:

2-APB, 2-氨基乙基二苯基硼酸酯, 2-氨基乙基联苯基硼酸酯, NSC 17107, 二苯基硼酸, 二苯基硼酸 2-氨基乙酯

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关于此项目

线性分子式:
(C6H5)2BOCH2CH2NH2
化学文摘社编号:
524-95-8
分子量:
225.09
UNSPSC Code:
12352103
NACRES:
NA.22
PubChem Substance ID:
57654145
EC Number:
208-366-5
Beilstein/REAXYS Number:
2942273
MDL number:
MFCD00014823
Assay:
97%
Form:
powder
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description

Drug Control: Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet

Quality Level

200

assay

97%

form

powder

drug control

Új pszichoaktív anyag / New psychoactive substance (Hungary), 78/2022. (XII. 28.) BM rendelet

storage temp.

−20°C

SMILES string

NCCOB(c1ccccc1)c2ccccc2

InChI

1S/C14H16BNO/c16-11-12-17-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10H,11-12,16H2

InChI key

BLZVCIGGICSWIG-UHFFFAOYSA-N

Application

可用作以下反应试剂：
  • 制备细胞凋亡诱导剂

  • Orai3（ORAI钙释放-激活钙调节因子3）蛋白活化剂
  • 抑制大鼠背根神经节神经元通过瞬时受体电位2通道的Ca2+ 流
  • 膜渗透SOCE（库调控钙入口）抑制剂

Biochem/physiol Actions

用于细胞内 IP3 诱导钙释放的膜渗透性调节剂。

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCH1285
BCCG3745
BCCF3928
BCCD7963
BCCC5729

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Mustafa Nazıroğlu et al.
The Journal of membrane biology, 241(2), 69-75 (2011-04-22)
Exposure to oxidative stress causes health problems, including sensory neuron neuropathy and pain. Rotenone is a toxin used to generate intracellular oxidative stress in neurons. However, the mechanism of toxicity in dorsal root ganglion (DRG) neurons has not been characterized.
Velasco-Bejarano, B.; et al.
Synlett, 921-921 (2007)
T Maruyama et al.
Journal of biochemistry, 122(3), 498-505 (1997-11-05)
The effects of a novel membrane-penetrable modulator, 2APB (2-aminoethoxy diphenyl borate), on Ins(1,4,5)P3-induced Ca2+ release were examined. 2APB inhibited Ins(1,4,5)P3-induced Ca2+ release from rat cerebellar microsomal preparations without affecting [3H]Ins(1,4,5)P3 binding to its receptor. The IC50 value (concentration producing 50%
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全球贸易项目编号

货号GTIN
D9754-5G04061835556670
D9754-10G04061835556649
D9754-1G04061835556656
D9754-25G04061835556663