365250
Gö 6976
≥95% (HPLC), protein kinase C inhibitor, solid
别名:
Gö 6976
选择尺寸
关于此项目
产品名称
Gö 6976, Gö 6976, CAS 136194-77-9, is a cell-permeable, reversible, and ATP-competitive inhibitor of PKC (IC50 = 7.9 nM for rat brain). Exhibits selectively for PKCα (IC50 = 2.3 nM) and βI (IC50 = 6.2 nM).
Quality Level
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
off-white
solubility
DMSO: 5 mg/mL
shipped in
ambient
storage temp.
2-8°C
SMILES string
[n]1(c2c3[n](c4c(c3c5c(c2c6c1cccc6)CNC5=O)cccc4)C)CCC#N
InChI
1S/C24H18N4O/c1-27-17-9-4-2-7-14(17)20-21-16(13-26-24(21)29)19-15-8-3-5-10-18(15)28(12-6-11-25)23(19)22(20)27/h2-5,7-10H,6,12-13H2,1H3,(H,26,29)
InChI key
VWVYILCFSYNJHF-UHFFFAOYSA-N
General description
Biochem/physiol Actions
PKC
Preparation Note
Other Notes
Wenzel-Seifert, K., et al. 1994.Biochem.Biophys.Res. Commun.200, 1536.
Martiny-Baron, G.M., et al. 1993.J. Biol. Chem.268, 9194.
Qatsha, K.A., et al. 1993.Proc.Natl.Acad.Sci. USA90, 4674.
Legal Information
Disclaimer
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
商品
Learn tips and tricks for how to properly use inhibitors including how to select the right inhibitor and how to plan experiments with inhibitors.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 365250-500UG | 07790788049614 |
| 365250-1MG | 04055977192018 |