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MABF31

Anti-Alpha Defensin-5 (HD5) Antibody, clone 8C8

Name: Anti-Alpha Defensin-5 (HD5) Antibody, clone 8C8
Brand: MM

clone 8C8, from mouse

别名:

defensin, alpha 5, Paneth cell-specific, defensin, alpha 5, preproprotein, defensin-5, defensin 5, Defensin, alpha 5

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关于此项目

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

8C8, monoclonal

Application:

IHC, WB

Citations:

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属性

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

8C8, monoclonal

species reactivity

human

technique(s)

immunohistochemistry: suitable, western blot: suitable

isotype

IgG2bκ

NCBI accession no.

NP_066290

UniProt accession no.

Q01523

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... DEFA5(1670)

说明

General description

10 kDa calculated

Human alpha defensin-5 (HD5) is one of six peptides belonging to the alpha defensin family. Defensins are small peptides involved in immunological defense against viral and microbial infections through either direct interaction with pathogens or in combination with other immune system factors. There are three subfamilies of defensins (α, β, and θ). α defensins are only observed in mammals and are mainly β-sheet structures. Alpha defensin-5 (HD5) is primarily expressed in the Paneth cells found within the small intestine, and has been shown to possess activity against both Gram-positive and Gram-negative microbes. Studies have shown alpha defensin-5 (HD5) to be a strong antagonist towards human Papillomavirus infection. It may also play a role Crohn’s disease.

Immunogen

Recombinant protein corresponding to human alpha defensin-5 (HD5).

Application

Anti-Alpha Defensin-5 (HD5) Antibody, clone 8C8 detects level of Alpha Defensin-5 (HD5) & has been published & validated for use in IH & WB.

Western Blot Analysis: 0.5 ug/mL from a previous lot detected alpha defensin-5 (HD5) in human small intestine tissue lysate. The urea-treated method is recommended instead of SDS page (Shen, B. et al., 2005).

Physical form

Format: Purified

Analysis Note

Evaluated by Immunohistochemistry in normal human tranverse colon tissue.

Immunohistochemistry Analysis: A 1:200 dilution of this antibody detected alpha defensin-5 (HD5) in normal human tranverse colon tissue.

Control
Normal human tranverse colon tissue

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c