Merck
CN
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文件

MATFLAGELLIN

Millipore

NEP Control Flagellin- PyroMAT® System MAT

Non-endotoxin pyrogen control of flagellin for use in monocyte activation test

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别名:
NEP, NEP Control
eCl@ss:
32160606

检测方案

≥95% (SDS-PAGE)

质量水平

用途

sufficient for 10 tests

特点

Non-endotoxin pyrogen control of flagellin for use in monocyte activation test

制造商/商品名称

PyroMAT®

应用

pharmaceutical
pyrogen testing

相容性

configured for PyroDetect System
configured for PyroMAT® System

运输

cooler

储存温度

−20°C

适用性

pyrogenic bacteria

相关类别

一般描述

The PyroMAT® System uses cryopreserved Mono-Mac-6 (MM6) human monocytic cells as a source of monocytes. The response to a full range of pyrogens, including endotoxins and non-endotoxin pyrogens (NEPs)is determined by the measurement of interleukin-6 (IL-6) produced by the Mono-Mac-6 cells using ELISA.
NEP control flagellin is a preparation of flagellin from Salmonella typhimurium and supplied in a lyophilized form. Flagellin is a non-endotoxin pyrogen (NEP) that activates the TLR5 receptor of monocytes and can be used as a positive control with the PyroMAT® System (Monocyte Activation Test for pyrogen detection).

特异性

TLR-5 agonist

应用

NEP control of flagellin can be used as a positive control with the PyroMAT® System. It is to be used for Product Specific Validation (PSV) and routine testing to show that the system can detect non-endotoxin pyrogen contaminants in pharmaceutical products.

特点和优势

Endotoxin-free product at concentration of use in MAT Purity: ≥ 95% (SDS-PAGE)

储存及稳定性

Store unopened vials at -20°C
Do not use unopened vials after expiration date
Store resuspended aliquots at -20°C
Shelf life of aliquots can be found on the technical datasheet

法律信息

PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

13 - Non Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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