410225
甘氨酸
ACS reagent grade, ≥98.5%, powder, crystals or granules
别名:
氨基乙酸, 甘氨酸
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关于此项目
线性分子式:
NH2CH2COOH
化学文摘社编号:
分子量:
75.07
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-272-2
MDL number:
Beilstein/REAXYS Number:
635782
产品名称
甘氨酸, ACS reagent, ≥98.5%
grade
ACS reagent
Quality Level
assay
≥98.5%
form
powder, crystals or granules
impurities
H2SO4, passes test (darkened), Hydrolyzable subsances, passes test
ign. residue
≤0.1%
color
white
pKa (25 °C)
(1) 2.35, (2) 9.60, 2.35
mp
240 °C (dec.) (lit.)
anion traces
chloride (Cl-): ≤0.005%, sulfate (SO42-): ≤0.005%
cation traces
NH4+: ≤0.005%, heavy metals: ≤0.002% (by ICP)
application(s)
peptide synthesis
functional group
amine, carboxylic acid
SMILES string
NCC(O)=O
InChI
1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChI key
DHMQDGOQFOQNFH-UHFFFAOYSA-N
Gene Information
rat ... Grin2a(24409)
General description
甘氨酸是最简单的氨基酸结构单元。
Application
甘氨酸用于全细胞膜片钳记录，以测量NMDA（N-甲基-D-天冬氨酸）内向电流。它还用作结晶学中的模型有机系统，展示新型声学雾化平台。
Biochem/physiol Actions
甘氨酸是非必需氨基酸。通过细胞膜的钙内流由甘氨酸门控通道介导。甘氨酸参与卟啉、嘌呤和丝氨酸的合成。它还可作为谷氨酸与NMDA（N-甲基-D-天冬氨酸）受体结合的竞争性激动剂。在快速增殖的癌细胞中，由于对氨基酸的需求增加，甘氨酸合成可能会增加。
脊髓中的抑制性神经递质，NMDA受体的变构调节器。
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存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Controversial Effects of D-Amino Acid Oxidase Activator (DAOA)/G72 on D-Amino Acid Oxidase (DAO) Activity in Human Neuronal, Astrocyte and Kidney Cell Lines: The N-methyl D-aspartate (NMDA) Receptor Hypofunction Point of View
Vinita Jagannath
Frontiers in Molecular Neuroscience (2017)
A Novel Acoustomicrofluidic Nebulization Technique Yielding New Crystallization Morphologies
Heba Ahmed
Advanced Materials, 30(3) (2018)
Amino acids: metabolism, functions, and nutrition
Guoyao Wu
Amino Acids, 37(1), 1-17 (2009)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 410225-1KG | 04065273586763 |
| 410225-250G | 04061835555116 |
| 410225-50G | 04061835555123 |