biological source
human (iPSC line)
form
frozen liquid
packaging
vial of 1 (contains ≥1 million cells)
technique(s)
cell culture | mammalian: suitable
shipped in
liquid nitrogen
storage temp.
-140 to -196°C
General description
Human iPSC-Derived Spinal Astrocytes. Required supplements for the final cell differentiation and maturation (sold separately): BX-2600-100uL, BX-2020-100uL. Specialized glia that are the majority of the central nervous system (CNS), astrocytes do not conduct electrical signals but promote the health of the CNS through regulating the blood-brain barrier (BBB), excess neurotransmitter clearance, and maintaining ion balance, and more. Related diseases: ALS, SMA, Spinal Cord Injury.
Application
Function: Spinal Astrocytes promote mature motor neuron activity. Co-culturing motor neurons with spinal astrocytes promotes maximal calcium influx within 10 days. Energy and structural support cell for spinal neurons and immune response. Exhibit earlier and higher levels of synchronous firing when co-cultured with spinal motor neurons.
Features and Benefits
Marker Expression and Morphology: Fully differentiated Spinal Astrocytes express key astrocyte markers GFAP (green) and S100β (red) at >90% and exhibit mature process-bearing morphologies (shown with a DAPI stain).
Labelling by the spinal-specific marker HOXB4 (red) with a Hoescht stain highlights the regional specificity of the Spinal Astrocytes.
Labelling by the spinal-specific marker HOXB4 (red) with a Hoescht stain highlights the regional specificity of the Spinal Astrocytes.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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