biological source
synthetic
Quality Level
form
powder
mp
147 °C (dec.) (lit.)
solubility
water: 50 mg/mL, clear, colorless to light yellow
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria, mycobacteria
mode of action
cell wall synthesis | interferes
storage temp.
−20°C
SMILES string
N[C@@H]1CONC1=O
InChI
1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
InChI key
DYDCUQKUCUHJBH-UWTATZPHSA-N
Gene Information
human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRINA(2907)
General description
Chemical structure: amino acid derivatives
Application
D-cycloserine has been used to inhibit serine hydroxymethyltransferase.
Biochem/physiol Actions
作用方式:抑制细胞壁生物合成(D-Ala 肽键形成)。同时可防止将D-Ala转化为L-Ala。抑菌性。
作用于 NMDA 谷氨酸能受体的甘氨酸调节位点的部分激动剂;抗革兰氏阴性细菌的抗生素。
干预方式:D-Ala转运干预。
作用于 NMDA 谷氨酸能受体的甘氨酸调节位点的部分激动剂;抗革兰氏阴性细菌的抗生素。
干预方式:D-Ala转运干预。
Other Notes
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.
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存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
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