D134
3,7-二甲基-1-炔丙基黄嘌呤
≥98% (HPLC), powder
别名:
3,7-Dimethyl-1-(2-propynyl)xanthine, DMPX
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关于此项目
经验公式（希尔记法）:
C10H10N4O2
化学文摘社编号:
分子量:
218.21
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 15 mg/mL, clear
SMILES string
CN1C(=O)N(CC#C)C(=O)c2c1ncn2C
InChI
1S/C10H10N4O2/c1-4-5-14-9(15)7-8(11-6-12(7)2)13(3)10(14)16/h1,6H,5H2,2-3H3
InChI key
IORPOFJLSIHJOG-UHFFFAOYSA-N
Gene Information
human ... ADORA2A(135), ADORA2B(136)
rat ... Adora1(29290), Adora2a(25369)
Application
3,7-Dimethyl-1-propargylxanthine (DMPX) has been used as an A2 -adenosine receptor (AR) antagonist:
- to study its effects on potential modulation of motor output elicited by epidural spinal stimulation (ESS)
- to study the role of A2a receptor in elevating cyclic adenosine monophosphate (cAMP) levels
- to study its effects on the cell viability of human gastric cancer cell line
Biochem/physiol Actions
3,7-Dimethyl-1-propargylxanthine (DMPX) is a caffeine analog and A2-selective adenosine receptor (AR) antagonist.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves