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Merck
CN

D4526

多塞平 盐酸盐

≥98% (GC), norepinephrine uptake inhibitor, powder

别名:

11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenz[b,e]oxepine hydrochloride

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关于此项目

经验公式(希尔记法):
C19H21NO · HCl
化学文摘社编号:
分子量:
315.84
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
214-966-8
MDL number:
Assay:
≥98% (GC)
Form:
powder
Quality level:
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产品名称

多塞平 盐酸盐, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder

Quality Level

assay

≥98% (GC)

form

powder

composition

Z-isomer, 15% , E-isomer, ~85%

color

white to off-white

solubility

1 M HCl: 50 mg/mL, H2O: soluble

originator

Boehringer Ingelheim

SMILES string

Cl[H].CN(C)CC\C=C1/c2ccccc2COc3ccccc13

InChI

1S/C19H21NO.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H/b17-11+;

InChI key

MHNSPTUQQIYJOT-SJDTYFKWSA-N

General description

Doxepin is used to treat chronic idiopathic urticaria, chronic pain and anxiety. Doxepin exhibits antiserotonergic properties.

Biochem/physiol Actions

Tricyclic antidepressant that is a more potent inhibitor of norepinephrine uptake than of serotonin uptake; antagonist at H1 histamine, muscarinic cholinergic, and α-adrenoreceptors.

Features and Benefits

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

顺式和反式异构体混合物


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Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges



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分析证书(COA)

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